Case studies
From research to practice: AI innovations implemented and validated in real clinical trial settings.
Operational Deployment of DocMemo for Accelerated Patient Recruitment
in early Alzheimer's Disease Programs
Context
Qairnel collaborated with a specialized clinical research network operating multiple sites across Florida and Pennsylvania. The sponsor sought to accelerate recruitment for two high-priority, late-phase clinical trials targeting patients with Early Alzheimer’s Disease (AD).
In the competitive landscape of AD recruitment, traditional methods often struggle with low screen-success rates and “database exhaustion.” The objective was to integrate DocMemo, Qairnel’s permanent screening infrastructure, to identify and qualify “pre-motivated” volunteers from the general population in real-time.
Challenge
The research network needed to overcome significant bottlenecks in patient identification under rigorous enrollment timelines, specifically addressing:
- Geographic Precision: Targeting populations within specific radii of trial sites in two different states.
- Quality vs. Quantity: Reducing the burden on site coordinators by delivering highly qualified leads rather than raw marketing inquiries.
- Reach: Accessing individuals with cognitive complaints who are not yet captured in existing clinical databases or traditional recruitment funnels.
- Execution Speed: Moving from contract signature to active referrals without the usual multi-week setup delays for custom web development and funnel setup.
Approach
Qairnel acted as a high-velocity recruitment partner, leveraging its pre-existing DocMemo infrastructure to bridge the gap between community-based cognitive concerns and clinical trial opportunities:
- Plug-and-Play Activation: Because DocMemo is a continuous, “always-on” platform, Qairnel bypassed the traditional ad-hoc setup phase. Targeted outreach was activated within 24 hours of contract signature, specifically optimized for the Florida and Pennsylvania site footprints.
- 24/7/365 Continuous Screening: Leveraged DocMemo’s proprietary screening engine to capture and assess individuals reporting cognitive complaints in real-time.
- Multidimensional Qualification: Beyond basic demographics, DocMemo process includes:
- Remote cognitive assessments and risk factor detection.
- Verification of core clinical inclusion/exclusion (I/E) criteria.
- Deep-dive assessment of participant motivations, perceptions, and potential barriers to trial participation.
- Seamless Site Integration: Delivery of decision-ready participant profiles directly to site staff, enabling immediate action.
Outcomes
The 4-week pilot demonstrated that a permanent screening infrastructure like DocMemo can fundamentally shift the efficiency of the recruitment funnel:
- Rapid Lead Generation: The first qualified leads were delivered to the sites in less than 48 hours from project initiation.
- High Conversion: Out of 24 qualified leads referred, 3 participants underwent the formal in-clinic screening visit within the first month.
- Early Randomization: The first patient was randomized into the trial by the second week of the collaboration. This represents a 33% screen-success rate, significantly outperforming the industry standard of <10% for similar outreach methods.
- Uncharted Audience Reach: Only one lead was previously known to the sites’ database. This confirms that DocMemo acts as a gateway to an exclusive population of potential participants, those proactively seeking answers but invisible to standard recruitment techniques.